The purpose of HC tests is to recognize the immunologic risk of a TR in the context of a possible donor. If Tx occurs between genetically different in
The purpose of HC tests is to recognize the immunologic risk of a TR in the context of a possible donor. If Tx occurs between genetically different individuals, the allogeneic graft (allograft) is identified as a foreign primarily owing to the difference between donor/TR MHC molecules that are known also as the HLAs. The developed immune response observed via 2 main mechanisms: T cell-mediated (cellular) response & AB-mediated (humoral) response. The current HC tests are focusing primarily on anticipating the AB-mediated alloimmune response.
The Snz to HLA Ag(s) and consequently the likelihood for Tx. The can calculate the likelihood of tx via interpreting the results of the SAB assay to recognize the specificity of the anti-HLA AB, combined with the known frequency of HLA Ag(s) within the donor cohorts. is a method enabling the clinician assessing a ptn's magnitude of