Loading ...

Followers

Lupus vulgaris

Lupus vulgaris (LV): a chronic & progressive pauci-bacillary type of cutaneous TB representing reactivated TB in subjects with moderate-high anti- TB

 

Lupus vulgaris (LV)

 

lupus vulgaris images lupus vulgaris treatment lupus vulgaris causes lupus vulgaris histopathology lupus vulgaris differential diagnosis lupus vulgaris medical definition lupus vulgaris medical term lupus vulgaris pictures

Lupus vulgaris (LV): a chronic & progressive pauci-bacillary type of cutaneous TB representing reactivated TB in subjects with moderate-high anti- TB immunity. LV may be developed due to direct extension of an underlying TB focus or though lymphatic/hematogenous spread. Alternate term: TB lupus.

 

Risk factors: LV is the most common type of cutaneous TB in Europe and certain zones in India. In contrary, scrofuloderma seems to be more observed in some tropical zones. LV can occur in ALL ages. It is not certain why females are 2-3 times more likely as compared to males to be involved. LV has also been observed in ptns with previous TB verrucosa cutis, scrofuloderma, and rarely as a sequela of BCG vaccination or primary inoculated TB. Despite the most commonly causing organism is M. TB, there’re documented cases related to M. bovis, & clinical picture is simulating LV related to M. TB. Subjects at risk for M. bovis LV are the resident in rural zones, contacting cattle, or consuming infected milk products.

 

Clinical presentation: clinical findings of LV are variable. Typical plaque presentation starts as a collection of discrete, red-brown papules with subsequent coalesce to be an indolent, asymptomatic plaque. The plaque gradually extends peripherally to reach 0.5-10 cm with central clearance & atrophy. Lesional borders may show serpiginous or verrucous quality. Hypertrophic, ulcerative, & vegetative form of LV can be also be seen. Lesions with secondary infection may show a seropurulent discharge with crust formation. In the West, LV often observed on the head & neck, while in tropical & subtropical zones, lesions are commonly seen on the lower limbs or buttocks. Similar to other granulomatous lesions, e.g., sarcoidosis & leprosy, diascopy (examining the lesion with compression via a glass slide) of non-hyperkeratotic areas of LV usually show a yellow-brown color known as an "apple jelly". However, it is difficult to observe with dark skin.

 

Dgx: LV is a paucibacillary type of cutaneous TB, & mycobacteria usually cannot be identified by biopsy or culture. However, Dgx supported by evident clinical & histopathologic pattern & +ve nucleic acid amplification (NAA) testing. Tuberculin testing can be also +ve. Histopathology may show tuberculoid granuloma + discrete, central caseation in upper dermis. Epidermis could be atrophied or acanthotic + excessive hyperkeratosis or pseudo-epitheliomatous hyperplasia.  Dermatoscopic testing may show well-focused, linear-branching telangiectasia on a diffuse/localized, structureless, yellow/orange background + whitish, reticular streaking.

 

DD: LV shares clinical findings with many disorders. Papular lesions should be DD from colloid milia, acne, & rosacea. Plaques may simulate deep fungal infection, Leishmania, late syphilitic infection, discoid lupus, tuberculoid leprosy, & psoriasis.                                    Course: with no ttt, lesion of LV persists & may grow to enormous size over years. Ulceration & destruction of tissues, e.g., nose, ears, & lips, could be seen > severe disfiguring.  Squamous cell carcinoma may develop in long-standing disorders. Rarely, basal cell carcinoma can be seen in long-standing LV locations.

COMMENTS

Name

Arabic window,5,Hemodialysis,24,My Publications,4,Peritoneal dialysis,14,Prevention of renal failure,63,Renal face,43,Renal Transplantation,57,TOP RECENT,38,
ltr
item
fedo: Lupus vulgaris
Lupus vulgaris
Lupus vulgaris (LV): a chronic & progressive pauci-bacillary type of cutaneous TB representing reactivated TB in subjects with moderate-high anti- TB
https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhB4i9vKYOnfRI9kYhfTJztyWn6Ml0X_77O6C-nTfwSoVpP6J1Tk6fS4gpWiZryXcgjXxtujEbzZO7gICneFBERO0IwnJb7iK86B44NOl5tqETyt4CioXHYEBU4SNlJ8riTPar0WX3oAL8/w320-h286/image.png
https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhB4i9vKYOnfRI9kYhfTJztyWn6Ml0X_77O6C-nTfwSoVpP6J1Tk6fS4gpWiZryXcgjXxtujEbzZO7gICneFBERO0IwnJb7iK86B44NOl5tqETyt4CioXHYEBU4SNlJ8riTPar0WX3oAL8/s72-w320-c-h286/image.png
fedo
https://www.fedokidney.com/2020/12/lupus-vulgaris.html
https://www.fedokidney.com/
https://www.fedokidney.com/
https://www.fedokidney.com/2020/12/lupus-vulgaris.html
true
8610857019469578230
UTF-8
Loaded All Posts Not found any posts VIEW ALL Readmore Reply Cancel reply Delete By Home PAGES POSTS View All RECOMMENDED FOR YOU LABEL ARCHIVE SEARCH ALL POSTS Not found any post match with your request Back Home Sunday Monday Tuesday Wednesday Thursday Friday Saturday Sun Mon Tue Wed Thu Fri Sat January February March April May June July August September October November December Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec just now 1 minute ago $$1$$ minutes ago 1 hour ago $$1$$ hours ago Yesterday $$1$$ days ago $$1$$ weeks ago more than 5 weeks ago Followers Follow THIS PREMIUM CONTENT IS LOCKED STEP 1: Share to a social network STEP 2: Click the link on your social network Copy All Code Select All Code All codes were copied to your clipboard Can not copy the codes / texts, please press [CTRL]+[C] (or CMD+C with Mac) to copy Table of Content