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Transplantation and Medications

Q.692. Many drugs can ppt. ARF in R.Tx., discuss?

 


﴾﴾III. Transplantation and Medications  ﴿﴿

 

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Allograft of the 
Renal transplantation

Q.692. Many drugs can ppt. ARF in R.Tx., discuss?

A. The following drugs  👉 are accused:

1. NSAID 🠞Functional pre-renal, esp. é hopovolemia, RASAvoid.                                                    2. ACE/ARB🠞Functional pre-renal, esp. é hopovolemia, RASAvoid early use.                                3. SMX/TMP: High dose TMP🠞🠟tub. Cr. secretion (no effect é GFR), well tolerated.                                                                                                                                                     4. Acyclovir/foscarnet🠞Tubular crystal deposition🠞Obstruction🠞ttt: good hydration.                      5. INFa 🠞Immune stimulatory effect 🠞Ac. Rj. 🠞use cautiously.                                                          6. Verapamil, Diltiazem, erythromycin, ketokenazol🠞🠟CNI metb.🠞🠝s. level.                                                                                                                                                              7. CNI: 🠞🠝Statin level 🠞Rhbdo. risk🠞use CNI é lower dose.  Monitor C.K., .. Pravastatin & Fluvastatin are less affected.

Q.693. Give general idea about the current immunosuppression?

A. I. Anti-T-cell receptor A.B.

    II. Glucocorticoids.

    III. Calcineurin inhibitors (C.N.I.s) : Csp. (Neural ) & Tacrolimus (Prograf ).

    IV. Target of Rapamycin, m(TOR) inhibitors, Sirolimus (Rapamycin).

    IV. Antiproliferative Ag.: MMF(Sp. Purine inhibitors)& Aza.(Non-sp. purine inhibitors).

Q.694. Specify anti-“T” cell receptor A.B.?

A. Twomain groups:                                                                                                                             I. Anti-lymphocytes A.B. targeting All T-cells 🠞 Non sp., targeting All T-cell, not just those reacting é allograft, it incl. two  ✌  main preparations:                       

   i. OKT3 (Orthoclone) 🠞 Mouse monoclonal A.B. agnst CD3 receptor Cx. on T-cells.

  ii. Polyclonal A.B.🠞 Rabbit (thymoglobin, rATG) or Horse (ATGAMأنغام الحصان), immunized é human lymphoid cells 🠞 multiple. A.B. agnst multiple leukocyte Ag.

Both i. & ii. are equally effective, but Polyclonal esp. (Rabbit thymoglobin) are  most effective/tolerated due🠞 more sustained depletion of reciptor lymphocytes.           

 * Indications:   

v Induction: additional initial im/m. thpy (1st 5-14 d.) e.g. DGF & high risk ptn.       

v  Reversal of Ac. Rejection.

II. Humanized/Chimeric Anti-IL2 receptors [monoclonal A.B.]: more specific im/m., because full IL2 receptors only expressed on👉 activated T. cells. Humanization or Chimerization of A.B.🠞 minimize recipient generation of anti-mouse A.B. (a problem in O.K.T3)🠞 prolongation of ½ life & drug efficacy.    

* Indications: Only as initial im/m. (induction thpy), Not for Ac. Rj..

* Members: Anti-CD 25 (anti IL2) recep. A.B.🠞

*      Basileximab. (Simulect).

*      Daclizumab. (Zanapax).

…. Well 😊 tolerated é minimal S.E. é induction thpy.

Q.695. How can Corticosteroids exert their action? What is the impact of glucocorticoid-free immunosuppression?

A. They’re the cornerstone in im/m. therapy. Tapering of the initial dose is continued until reaching a maintenance of 5-10 mg/d.

* Mechanism of action: Anticytokine” (incl. IL.2) + Antinflammatory effects.

* S.E. : [Glucose intolerance- H.T.- Hyperlipidemia- Osteoporosis & necrosis -Myopathy- Growth retardation in children- cosmetic & neuropsychiatric effects].

A.The 10-y. outcomes of a glucocorticoid avoidance strategy foll. R.Tx. have been reported. Among 1241 low-risk adult Tx. recipients receiving allografts betw. 1999 & 2010, in whom prednisone ws discontinued within one w. after Tx., both ptn. & graft survival were comparable to national data rep. by the Scientific Registry of Tx. Recipients in 2009. 

Q696. Describe the role & S.E. of calcineurin inhibitors (CNIs.)?

A. Calcineurin inhibitors (CNIs.):

I.    Csp 🠞🠋 CALCINEURIN (Key enzyme for T-cell activation) 🠞🠋of IL2. & other molecules necessary for “T cell” activation.

S.E.: [Nephrotoxicity, Ac. & ch. Rj., G.H.H. (Glucose intolerance- H.T.- Hyperlipi-demia)- Cosmetic effects (Hirsutism). ].

II.    Tacrolimus: Same mechanism & S.E. as Csp, but More diabetogenic & Less [ H.T.- Hyper-lipidemic & cosmetic effects].

Disadv.: More (Nephrotoxic & neurotoxic)- more D.M. , more G.I. esp.  é MMF.

Q.697. What about antiproliferative group?

A. Antiproliferative agents:

i.    Aza: a purine analogue 🠞🠟DNA & RNA synthesis🠞🠟“T”-cell & “B” lymphocytic replication. S.E.: 🠞[B.M. suppression- rarely hepatitis & pancreatitis.].     N.B.: Concurrent “Allopurinol” use 🠞 Fatal B.M. suppression.,💀  as Xanthi-ne Oxidase, responsible for Aza metab., will be suppressed by Allopurinol 🠞🠝🠝s. level of Aza🠞 Sev. B.M. suppressionSo, Reduce Aza dose by 75 %.

ii.    MMF: Inhibit De Novo pathway of purine biosynthesis (more selective)      🠞          

🠋🠋 Lymphocytic replication. It hs the foll. effects:   

1)   Block T & B cell proliferation. 

2)   Inhibit A.B. formation.

3)   Dcr. expression of “adhesion molecules”. 

4)   Reversible inhibition of “Inosine monophosphate dehydrogenase”.                                                                                                                                                                                                                                                                S.E.:Ö[n. & v.- G.I. upset.- B.M. suppression- more CMV. tissue invasion].

Q.698. What are m. T.O.R.s.?

A. Sirolimus (Rapamycin):[Siriolimus-F.K.B.P.(f. k.- binding protein) Cx.], binds & inhibits a kinase called (T.O.R.)=target of rapamycin🠞🠋lymphocytic proliferation.

Both CNIs & Siros 🠞 are mtb.by “Cytochrome P 450 🠞 many drug interactions. “Rapamycin” most appropriately used as:       

1) CNIs-sparing drug: (stopping CNIs improves GFR) &   in

2) Ptn é  Neoplasia.

Q.699.What are the possible side effects?

S.E.🠞[B.M. suppression-Hyperlipidemia-Interstitial pneumonitis-🠝Csp. toxicity.].

Q.700. How to start induction immunosuppressive therapy in R.Tx. in adults?

A. Im/m. for R. allog. recipientis recommended but optimal reg. is unclear. Induction:is recomm. for R. allograft, it consists of: [A.B.+standard im/m.] rather thn standard im/m. thpy alone. Caucasian recip. of two haplotypeidentical L.R.A. don’t require induction thpy é A.B. thpy given the dcr. immunologic risk of Ac. Rj.. A.B.s incl. [rATG- thymoglobulin, ATGAM, alemtuzumab, OKT3 & two IL-2 receptor A.B.: basiliximab & daclizumab].  Ptns at incr. risk of Rj., start of rATG-thymoglobulin rather thn IL-2 receptor antagonist is recommended. Ptns not at increased risk of Rj., giving of rATG-thymoglobulin rather thn IL-2 receptor antagonist is suggested. If rATG-thymoglobulin cannot be administered, IL-2 receptor A.B. is recommended.


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Transplantation and Medications
Q.692. Many drugs can ppt. ARF in R.Tx., discuss?
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https://www.fedokidney.com/2020/10/transplantation-and-medications.html
https://www.fedokidney.com/
https://www.fedokidney.com/
https://www.fedokidney.com/2020/10/transplantation-and-medications.html
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