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ACUTE KIDNEY INJURY (ACUTE RENAL FAILURE) IN PREGNANCY

Many complications associated with pregnancy may induce AKI (acute kidney injury or acute renal failure).

ACUTE KIDNEY INJURY (ACUTE RENAL FAILURE) IN PREGNANCY

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Many complications associated with pregnancy may induce AKI (acute kidney injury or acute renal failure). In the early period of pregnancy, pre-renal disease (fluid loss and dehydration) or acute tubular necrosis may follow hyperemesis gravidarum (persistent vomiting) or septic abortion. In the late pregnancy period, acute renal failure may induced by preeclampsia, thrombotic microangiopathies, acute fatty liver of pregnancy, renal cortical necrosis, pyelonephritis, urinary tract occlusion or kidney stone disease.   

The finding of low platelet count (thrombocytopenia) and anemia (low hemoglobin) with acute kidney injury may be induced by either thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) or severe preeclampsia with the HELLP syndrome. A full detailed history with a complete battery of investigation will help differentiation these disorders. Therapy of preeclampsia associated with HELLP syndrome can be induced by delivery institution.